From Gloucestershire, a distant relation of Oliver Cromwell. Supported the Parliamentary cause in the English Civil War. He was a General at Sea, major-general. One of the Commissioners for Charles I's trial and one of the signatories on the death warrant.
When Charles II was restored to the throne he ordered the disinterment of the bodies of Oliver Cromwell and his supporters, including Deane, and their reburial in an unmarked pit in St Margaret's churchyard, Westminster.